Type 1 interferon perturbates clonal competition by reshaping human blood development
C. Lama, D. Isakov, S. Rosenberg, M. Quijada-Alamo, M. S. Saurty-Seerunghen, S. Moein, T.-A. Abera, O. Sakaguchi, M. Totwani, G. Freed, C.-L. Poon, N. Parghi, A. Kubas-Meyer, A. X. Xie, M. Omar, , A. S. Nam
The paper investigates how type 1 interferon affects clonal competition in human blood development by altering HSC differentiation states and clonal fitness.
bioRxiv · Sep 28, 2022Cancer Biology