Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for real-world antibody specificity prediction
P. A. Robert, R. Akbar, R. Frank, M. Pavlovic, M. Widrich, I. Snapkov, A. Slabodkin, M. Chernigovskaya, L. Scheffer, E. Smorodina, P. Rawat, B. B. Mehta, M. H. Vu, I. Froberg Mathisen, A. Prosz, , V. Greiff
The paper introduces Absolut!, a software suite generating synthetic antibody-antigen structures to benchmark machine learning methods for antibody specificity prediction.
bioRxiv · Jul 6, 2021Immunology