Immunogenicity and Structure of a Stabilized HIV -1 clade C Env from a Pediatric Elite neutralizer in Complex with an Autologous bnAb
Swarandeep Singh, Sanjeev Kumar, Arnab Chatterjee, Lakshay Malhotra, Muneeb Pervez, Abdul Rahman, Ifrah Andrabi, Bapan Mondal, Sanket Katpara, Shaifali Sharma, Harsh Bhakri, Anjli Gaur, Tanu Bansal, V. N. Iyer, Abdul Wahid Hussain, , Kalpana Luthra
This study investigates the immunogenicity and structure of a clade C HIV-1 Env trimer from a pediatric elite-neutralizer, showing it elicits strong autologous neutralizing antibodies and reveals key neutralizing epitopes.
bioRxiv · Apr 26, 2025 · PreprintImmunology