Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia
Jennifer Hsiao‐Nakamoto, Chi‐Lu Chiu, Lawren A. VandeVrede, Ritesh Ravi, Brittany Vandenberg, Jack De Groot, Buyankhishig Tsogtbaatar, Meng Fang, Paul Auger, Neal S. Gould, Filippo Marchioni, Casey A. Powers, Sonnet S. Davis, Jung H. Suh, Jamal I. Alkabsh, , Fen Huang
This study identifies and characterizes lysosomal, glial, and neurodegenerative biomarkers in cerebrospinal fluid and plasma from FTD patients, revealing their correlation with disease severity and tissue changes.
bioRxiv · Feb 9, 2024 · PreprintNeuroscience