High Resolution Multi-Pass Astral Analyzer Quantification Enables Highly Multiplexed 35-Plex Tandem Mass Tag Proteomics
Hamish Stewart, Steven R. Shuken, Christopher Rathje, Julia Kraegenbring, Martin Zeller, Tabiwang N. Arrey, Bernd Hagedorn, Eduard V. Denisov, Robert Ostermann, Dmitry Grinfeld, J. Petzoldt, Daniel Mourad, Philipp Cochems, Florian Bonn, Bernard Delanghe, , Steven P. Gygi
This paper introduces a high-resolution multi-pass Astral analyzer mode for TMT proteomics, enabling 35-plex quantification with improved depth and precision.
bioRxiv · Feb 26, 2026 · PreprintBiochemistry