NeuroscienceJournal of the American Chemical SocietyPeer-reviewed
A new chemoenzymatic semisynthetic approach provides novel insight into the role of phosphorylation beyond exon1 of Huntingtin and reveals N-terminal fragment length-dependent distinct mechanisms of aggregation
Kolla Rajasekhar, Pushparathinam Gopinath, Jonathan Ricci…·Hilal Ahmed Lashuel
This paper investigates the aggregation mechanisms of different N-terminal Htt fragments and introduces a chemoenzymatic method for site-specific phosphorylation beyond Httex1.
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