BiochemistrybioRxivPreprint
Dynamic hotspots in the Uba7 UFD direct UbcH8 recognition
Çağdaş Dağ, Mahil Lambert, Alp Eren Kazar…·Emine Sonay Elgin
This paper presents the NMR structure and functional analysis of the Uba7 UFD domain and its interaction with UbcH8, revealing structural flexibility and key residues critical for E2 recognition in the ISGylation pathway.
DOI 10.1101/2025.06.14.659664