NeurosciencebioRxivPreprint
ASH1L REGULATES THE STRUCTURAL DEVELOPMENT OF NEURONAL CIRCUITRY BY MODULATING BDNF/TrkB SIGNALING IN HUMAN NEURONS
Seon Hye Cheon, Allison M. Culver, Anna M. Bagnell…·Sofia B. Lizarraga
This study shows ASH1L regulates neuronal connectivity by modulating BDNF/TrkB signaling through its interaction with PRC2 in human neurons, linking ASH1L mutations to autism pathogenesis.
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