NeurosciencebioRxivPreprint
Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease
Kevan D. Shah, Rishi Bedi, Alex Rogozhnikov…·G. Sean Escola
This paper develops an automated system to scale patient-derived brain organoids, revealing consistent donor and batch effects and demonstrating reproducible disease phenotypes in tuberous sclerosis models.
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