Molecular BiologybioRxivPreprint
A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS
Katherine E. Irwin, Pei Jasin, Kerstin E. Braunstein…·Philip C. Wong
The paper identifies a fluid biomarker, cryptic HDGFL2, that detects early TDP-43 splicing repression in pre-symptomatic ALS patients.
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