BiochemistrybioRxivPreprint
Asymmetric DNA targeting by RNA-guided TIGR-Tas systems
Kaoling Guran, Nathan M. Appleby, Boyu Huang…·David Ward Taylor
This study investigates how TIGR-Tas systems recognize and cleave DNA targets, revealing asymmetric target engagement and coordinated cleavage across both RNA-DNA heteroduplexes.
DOI 10.64898/2026.08.11.744272