Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression
Tanjina Kader, Maia Zethoven, Sakshi Mahale, Hugo Saunders, Lauren Tjoeka, Rebecca Lehmann, Madawa W Jayawardana, Jia‐Min Pang, Dorothea Lesche, Neeha Rajan, Timothy J. Semple, Jue Er Amanda Lee, Richard Lupat, David J. Byrne, Siobhan Hughes, , Kylie L. Gorringe
The paper analyzes paired breast carcinomas to determine if recurrences are clonal or new tumors, finding 7% are non-clonal by whole exome sequencing.
The Journal of Pathology · Oct 30, 2025Peer-reviewedCancer Biology