GenomicsNature CommunicationsPeer-reviewed
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Alvaro Barbeira, Scott P. Dickinson, Rodrigo Bonazzola…·Benjamin J. Strober
The paper develops S-PrediXcan to compute gene expression associations from GWAS summary data and applies it to 44 GTEx tissues and 100+ phenotypes, finding tissue-specific effects and colocalized associations.
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