Pharmacology & ToxicologybioRxiv
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells
M. A. Fischer, A.-H. M. Mustafa, K. Hausmann…·O. H. Kramer
This paper synthesizes novel HDAC inhibitors that show nanomolar activity against class I HDACs and induce apoptosis while constraining autophagy in leukemic cells.
DOI 10.1016/j.jare.2023.07.005