BiochemistrybioRxivPreprint
Computational Assessment of Circularization Impact on Saxitoxin G-quadruplex Aptamer Performance
Siyi Gao, Bowen Deng, Dingyuan Cheng…·Mingjuan Sun
The paper develops a computational method to guide the cyclization of saxitoxin aptamers, showing that circular aptamers have higher affinity and improved survival in mice.
DOI 10.1101/2025.05.05.652042