Author

J. B. Rottman

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. K. Shalek· 1 shared C. McGuckin· 1 shared E. E. Ho· 1 shared F. Alvarez-Calderon· 1 shared F. Eng· 1 shared J. Charles· 1 shared J. Kaminski· 1 shared J. Lane· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. K. Shalek

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintSep 28, 2023

B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients

J. Kaminski, R. A. Fleming, F. Alvarez-Calderon…·U. Gerdemann

The paper identifies a novel mechanism where CAR-T cell therapy activates CD8+ cytotoxic bystander T cells in non-human primates and patients, showing they can kill leukemic cells independently of TCR.

DOI 10.1101/2023.09.28.559936

non-human primatehuman