ImmunologybioRxivPreprint
Non-canonical caspase-8 activation by cathepsin B drives anti-inflammatory human macrophage polarization
Emeline Kerreneur, Paul Chaintreuil, Chloe Delaby…·Arnaud Jacquel
This study identifies cathepsin B as a novel upstream activator of non-apoptotic caspase-8, driving anti-inflammatory macrophage polarization and differentiation.
DOI 10.1101/2025.08.22.671722