NeuroscienceNature CommunicationsPeer-reviewed
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference
Alexandra L. Young, Razvan Valentin Marinescu, Neil P. Oxtoby…·Ronald G. Thomas
This paper introduces SuStaIn, a machine learning method that identifies disease subtypes and their temporal progression from cross-sectional data, improving prediction of diagnostic conversion in neurodegenerative diseases.