Cell BiologybioRxivPreprint
Human pluripotent stem cell-derived intestinal epithelial cells maintain small intestine-specific functions over time, even with repeated cell division
Junlong Chen, So Kuramochi, Shinichiro Horiuchi…·Akihiro Umezawa
This study compares drug metabolic capacity and cytotoxicity of Caco-2 cells, cryopreserved enterocytes, and stem cell-derived intestinal epithelial cells to identify a better model for drug discovery.
DOI 10.1101/2025.02.17.638577