Author

Mark Temper

Hadassah Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert GrinshpuniD· 2 shared Aviad ZickiD· 2 shared Ayala Hubert· 2 shared Azzam Salah· 2 shared Jonathan E. CoheniD· 2 shared Myriam Maoz· 2 shared Tamar PeretziD· 2 shared Ahinoam Gugenheim· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Albert GrinshpunORCID

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2 papers

Recent·Most cited

Improved deconvolution of circulating tumor DNA from ultra-low-pass whole-genome methylation sequencing using CelFiE-ISH

Efrat Katsman, Sara Isaac, Alaa Darwish, Myriam Maoz, Michal Inbar, MazalTov Marouani, Irene Unterman, Ahinoam Gugenheim, Nada Salaymeh, Shatha Abu Khdeir, Beatrice Uziely, Tamar Peretz, Luna Kaduri, Ayala Hubert, Jonathan E. Cohen, , Amir Eden

This study improves ctDNA deconvolution in ULP-WGS data using CelFiE-ISH, achieving lower cancer fraction detection limits than CNA benchmarks.

bioRxiv · Apr 18, 2026 · PreprintGenomics

ChIP-seq of plasma cell-free nucleosomes identifies cell-of-origin gene expression programs

Ronen Sadeh, Israa Sharkia, Gavriel Fialkoff, Ayelet Rahat, Jenia Gutin, Alon Chappleboim, Mor Nitzan, Ilana Fox-Fisher, Daniel Neiman, Guy Meler, Zahala Kamari, Dayana Yaish, Tamar Peretz, Ayala Hubert, Jonathan E. Cohen, , Nir Friedman

The paper introduces cfChIP-seq to analyze cell-free nucleosomes and shows it can detect disease-related transcriptional changes and patient-specific features in cancer.

Nature Biotechnology · Jan 11, 2021Peer-reviewedMolecular Biology