BiochemistryRedox BiologyPeer-reviewed
FUNCTIONAL ANALYSIS OF BIPARTITE NRF2 ACTIVATORS THAT OVERCOME FEEDBACK REGULATION FOR AGE-RELATED CHRONIC DISEASES
Dmitry M. Hushpulian, Navneet Ammal Kaidery, Priyanka Soni…·Bobby Thomas
This paper identifies HPPE as a bipartite Nrf2 activator that overcomes feedback regulation by inhibiting Bach1, showing potential for treating age-related neurodegeneration.
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