GenomicsiSciencePeer-reviewed
Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer
Angela B. Florio, James B. Smadbeck, Sarah H. Johnson…·George Vasmatzis
The paper investigates the functional impact of the HyperDuplication GenomoPhenotype in high copy number endometrial cancer, showing it enhances tumor fitness and therapy resistance through coordinated duplication of oncogenes.
DOI 10.1016/j.isci.2025.112850