Cancer BiologyMolecular OncologyPeer-reviewed
PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and Tamoxifen in a luminal A breast cancer model
Luisa E. Schwarzmüller, Janina Müller, Efstathios–Iason Vlachavas…·Stefan Wiemann
This study shows PAK1 activation leads to different resistance mechanisms against Tamoxifen and aromatase inhibitors in luminal A breast cancer by affecting apoptosis and proliferation through distinct pathways.
2 citations