Discover, rate, and discuss biology preprints.

This study shows particle-only gECM wafers match hydrogel wafers in mechanical and biological performance without needing secondary polymers.

This paper demonstrates T cells can deliver genome editing machinery to target cells via programmable intercellular interactions.

This paper develops a biomimetic spinal model to study axial mechanobiology and multi-segment coupling, enabling time-dependent adaptations and tissue maturation in vitro.

This study examines snake venom fluidic properties and develops non-toxic mimics to model venom flow for biomedical and evolutionary research.

This study shows that deep UV treatment increases the surface stiffness of soft silicones without affecting their bulk properties, as measured by nanoindentation and spectroscopy.

The paper identifies stress granule coarsening as a critical factor in cardiac electrophysiological dysfunction under oxidative stress.

This study evaluates consumer acceptance of different burger formulations by combining sensory evaluation and texture analysis, finding that moistness and meatiness are key factors influencing preference.

The paper screens 1,243 intracellular domains to identify ELMs and their combinations that influence CAR T-cell immunophenotype differentiation.

This study develops an in vitro intracranial aneurysm model with cardiovascular flow to investigate endothelial remodelling and identifies cytokine signatures as potential biomarkers for IA remodelling.

This paper develops a multi-modal flow phantom for PET and spectral CT to improve blood flow quantification by enabling tunable perfusion imaging.

This paper introduces a hydrogel-based biosensor that accelerates bacterial interaction with reporter molecules through engineered transport, achieving faster and more accurate detection of infections and antimicrobial susceptibility.

This paper develops a microfluidic platform to profile drug responses in NSCLC patient-derived organoids, showing that microenvironmental cues affect therapeutic responses and resistance mechanisms.

This paper develops a biodegradable nanoparticle-in-implant platform for sustained and light-boosted pirfenidone delivery to treat vocal fold fibrosis.

This paper introduces APQ, a pore-resolved platform for quantifying amyloid aggregation and amplification, revealing population-level structural insights beyond conventional ThT assays.

The paper introduces a microfluidic system for long-term high-resolution imaging of organotypic brain slices to study neural responses to glutamate.

This paper introduces MIRACLES, a method to image cell membrane potential dynamics using vibrational optoacoustic detection, and demonstrates its application in monitoring glucose-stimulated insulin secretion in beta-cells.

This study quantifies parasitic losses in UHF MRI receive coils and shows how they reduce predicted SNR, providing guidance for improving coil design.

This paper develops ovoprotein microgels for bioprinting that are structurally adaptive and biologically instructive, enabling vascularized and mineralized tissue constructs.

This paper compares deep learning models for improving 1H MRSI reconstruction, finding that U-Net outperforms MultiNet in reducing lipid artifacts and improving metabolite map fidelity.

This paper introduces DSI, a noninvasive ultrasound method to monitor coagulation and thrombolysis by tracking speed-of-sound shifts, and shows it can quantify clot formation and lysis in various biological systems.