Isotonic tartrazine is sufficient to improve transscleral penetration of optical coherence tomography
The paper shows that isotonic tartrazine improves OCT penetration without increasing ocular toxicity compared to hyperosmolar concentrations.
363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
The paper shows that isotonic tartrazine improves OCT penetration without increasing ocular toxicity compared to hyperosmolar concentrations.
Nicolas Buitrago, Josefina Brau, Jerzy O. Szablowski
This paper models synthetic serum markers to determine the theoretical limits of temporal resolution and precision in monitoring gene expression through blood draws.
Juan González‐Valdivieso, Rafael R. Castillo, Aleixandre Rodrigo‐Navarro…·Patricia Rico
This study shows NaBC1 enhances myoblast adhesion and polarization by interacting with fibronectin-binding integrins and modulating mechanotransduction.
Sarah M. Rock, Maria C. Alvarez, Ethan B. Schonhaut, Jesse C. Dean
This study examines how hip abductor vibration and surface translation affect mediolateral sway at low frequencies, finding that vibration increases sway above 0.5 Hz while translation causes more widespread effects.
Thibault Helleputte, Thomas Cornet, Ahmed Kanfoud…·Gaël de Lannoy
This paper addresses challenges in implementing chemometrics models for bioprocesses by combining spectrometry data, machine learning, and domain knowledge to improve model performance and scalability.
Yihan Wang, Xuesen Xu, Dong Wang
This study shows that transplanting fragmented intestinal organoids and crypts rectally promotes mucosal regeneration in DSS-induced colitis in immunocompetent mice.
Victor Yu, Perry Demsko, Roger Castells‐Graells…·Joseph B. Alzagatiti
This paper introduces Plica-1, a physics-based method for predicting large symmetric protein complex structures, achieving high accuracy and speed.
Raphael S. Knecht, Duncan M. Morgan, Matthias R. Kollert…·Georg N. Duda
This study shows that ECM viscoelastic properties in bone fracture hematoma influence macrophage polarization, with high stress relaxation time promoting pro-inflammatory and low promoting anti-inflammatory responses.
Qiang Jiang, Kai Su, Guangnan Li…·Xin Zhiguo Li
This study identifies temporal mismatch between mRNA delivery and spermatogenesis as a barrier to functional rescue, showing that sustained expression aligned with developmental timing enables recovery in genetic infertility models.
Paola Larrauri Aguilar, Guillermo García Contreras, Gonzalo Cabrera…·Cristóbal Briceño
The paper detects Cryptosporidium parvum in invasive beavers in southern Tierra del Fuego, Chile, highlighting their potential role as zoonotic pathogen reservoirs.
Royston K. Y. Tan, Swati Sharma, Anita Sook Yee Chan…·Michaël J. A. Girard
This study investigates the structural contribution of Bruch's membrane and sclera to the ocular wall by comparing their biomechanical properties under tension.
Mirko Luoni, Serena Gea Giannelli, Stefano Parracino…·Vania Broccoli
This paper develops AAV-STITCH, a method to target neuroblastoma cells using anti-GD2 ScFv coupled to AAV capsids, showing selective transduction and tumor suppression in mouse models.
Mamiko Suzuki, Masahiro Saito, Takuya Ueda…·Nobutake Hosoi
This study investigates how mice regulate body resonance and avoidance behavior during whole-body vibration across different axes, revealing axis-specific neuro-musculoskeletal control mechanisms.
Sunil Kumar, Rohit Kapila, Arpita Panda…·Subinoy Rana
This paper demonstrates biofuel-driven supramolecular nanowires with tunable conductance, showing n-type behavior and reversible conductance switching.
Amanzhol Kurmashev, Isabel Sorg, Julia Alicia Boos…·Christoph Dehio
This paper develops a 3D human urothelial model to study UTI dynamics and therapeutic responses in real-time.
Yongjie Zou, Haonan Niu, Bin Zhao…·Chengyu Li
This paper introduces MindSight, a deep learning algorithm for cortical electrical stimulation to improve visual restoration, showing better performance in visual perception tasks with macaque monkeys.
Christian G. Figueroa‐Espada, Hannah C. Geisler, Ryann A. Joseph…·Michael J. Mitchell
This study develops anti-CD38 lipid nanoparticles for targeted mRNA delivery to multiple myeloma cells, improving tumor targeting and reducing hepatic accumulation.
Adrienne E. Widener, Cameron T. Manson, Jessie M. Barra…·Edward A. Phelps
This study develops a CD3-functionalized hydrogel to protect stem cell-derived beta cells from immune rejection in diabetes therapy.
Wenbo Wang, Simran Swain, Jaeyong Lee…·Jia Liu B
Agentic Lab integrates AI agents with physical lab operations to improve reproducibility in cell and organoid research by autonomously generating protocols and analyzing experimental data.
Saskia Eckert, Christian Kassasseya, Morgane Garreau…·Pablo Bartolucci
This study develops an additively manufactured carotid artery model to simulate sickle cell disease vasculopathy, validated with clinical imaging and mechanosensitive cells.