Amanzhol Kurmashev

This study uses human colonic organoids to reveal how Enterococcus faecalis adapts to intestinal mucus, identifying key fitness determinants and colonization strategies not observed in vitro or in vivo.

The paper develops genetically-encoded biosensors to monitor antibiotic concentrations inside bacterial cells and tissues in real-time, revealing antibiotic exposure dynamics and penetration in infection models.

This paper develops a 3D human urothelial model to study UTI dynamics and therapeutic responses in real-time.

The paper introduces a microphysiological platform for culturing transwell-based lung tissues, enabling high-resolution live-imaging of airway infections and tissue responses.