β-adrenergic signaling modulates cancer cell mechanotype through a RhoA-ROCK-myosin II axis
T.-H. Kim, E. Vazquez-Hidalgo, A. Abdou, X. H. M. Tan, A. Christodoulides, C. M. Farris, P. Y. Chiou, E. K. Sloan, P. Katira, A. C. Rowat
This study identifies a β-adrenergic signaling pathway that modulates cancer cell mechanotype via RhoA-ROCK-myosin II axis, increasing stiffness and invasion.
bioRxiv · Sep 23, 2019 · PreprintCancer Biology