Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer
J. M. Vahrenkamp, C.-H. Yang, A. C. Rodriguez, A. Almomen, K. Berrett, A. N. Trujillo, K. P. Guillen, B. E. Welm, E. A. Jarboe, M. M. Janat-Amsbury, J. Gertz
The paper investigates the interaction between glucocorticoid receptor (GR) and estrogen receptor α (ER) in endometrial cancer, finding that GR expression correlates with poor prognosis and that their combined activity alters gene expression and genomic binding.
bioRxiv · Mar 7, 2018Cancer Biology