Prevalence study of cellular capsid-specific immune responses to AAV2, 4, 5, 8, 9 and rh10 in healthy donors
R. Xicluna, A. Avenel, C. Vandamme, M. Devaux, N. Jaulin, C. Couzinie, J. Le Duff, A. Charrier, M. Guilbaud, O. Adjali, G. Gernoux
The paper assesses T cell immunity to various AAV serotypes in healthy donors, finding AAV9 has the highest prevalence of pre-existing cellular immunity.
bioRxiv · Dec 20, 2023Immunology