Taxane induces attenuation of the CXCR2/BCL-2 axis and sensitize prostate cancer to platinum-based treatments
V. Ruiz de Porras, X. C. Wang, L. Palomero, M. Marin-Aguilera, A. Indacochea, N. Jimenez, B. Mellado, S. Bystrup, C. Sole-Blanch, J. M. Piulats, J. F. Suarez, J. C. Pardo, E. Martinez-Balibrea, A. Aytes, A. Font
This paper identifies that taxane treatment reduces CXCR2 and BCL-2 in mCRPC, making tumors more sensitive to platinum-based therapies.
bioRxiv · Jan 20, 2020 · PreprintCancer Biology