Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity
A. Bakunts, A. Orsi, R. Sitia, E. van Anken, M. Vitale
This study shows that IRE1α requires multiple dimers to undergo cross-phosphorylation and activate its RNase activity during ER stress.
bioRxiv · Dec 18, 2023Cell Biology