Two types of human TCR differentially regulate reactivity to self and non-self antigens
A. Trofimov, P. Brouillard, J.-D. Larouche, J. Seguin, J.-P. Laverdure, A. Brasey, G. Ehx, D.-C. Roy, L. Busque, S. Lachance, S. Lemieux, C. Perreault
The paper identifies two distinct TCR types in humans, differing in origin, function, and reactivity to self and non-self antigens, with implications for immunity and disease.
bioRxiv · Apr 27, 2022Immunology