Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
D. Alonso-Gil, A. Cuadrado, D. Gimenez-Llorente, M. Rodriguez-Corsino, A. Losada
The paper investigates the differential requirements of NIPBL for cohesin-STAG1 and cohesin-STAG2, showing NIPBL is not required for initial cohesin loading but is essential for loop extrusion and stabilization of cohesin-STAG2 at CTCF sites.
bioRxiv · Nov 29, 2022 · PreprintCell Biology