Increased efficacy of histone methyltransferase G9a inhibitors against MYCN-amplified Neuroblastoma
J. Bellamy, K. Malik, M. Szemes, Z. Melegh, A. Dallosso, M. Kollareddy, D. Catchpoole
This study shows G9a inhibitors are more effective against MYCN-amplified neuroblastoma, with G9a depletion triggering apoptosis specifically in these cells.
bioRxiv · Nov 22, 2019Cancer Biology