Evolutionary BiologybioRxivPreprint
Human genetic adaptation related to cellular zinc homeostasis
A. Roca-Umbert, J. Garcia-Calleja, M. Vogel-Gonzalez…·E. Bosch
This paper identifies directional selection on SLC30A9 haplotypes in Africa and East Asia, showing a gain-of-function variant in ZnT9 linked to mitochondrial metabolism and neuropsychiatric traits.
DOI 10.1101/2022.06.29.498106