A Network-based Transcriptomic Landscape of HepG2 cells to Uncover Causal Gene Cytotoxicity Interactions Underlying Drug-Induced Liver Injury
L. Wijaya, A. Gabor, I. Pot, L. v. der Have, J. Saez-Rodriguez, J. L. Stevens, S. E. Le Devedec, G. Callegaro, B. v. de Water
This study uses network-based transcriptomic analysis of HepG2 cells exposed to DILI compounds to identify causally linked genes involved in drug-induced liver injury.
bioRxiv · Jan 16, 2023 · PreprintPharmacology & Toxicology