Cell culture evolution of a HSV-1/VZV UL34/ORF24 chimeric virus reveals novel functions for HSV genes in capsid nuclear egress
R. J. Roller, T. Hassman, A. Haugo-Crooks
This study uses cell culture evolution to identify HSV genes that functionally interact with pUL34, revealing new roles for ICP22 in nuclear lamina disruption and ICP4 in capsid nuclear egress.
bioRxiv · Jun 18, 2021Microbiology