Author

A. K. Hedger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Ali· 1 shared A. N. Matthew· 1 shared C. A. Schiffer· 1 shared D. N. Rao· 1 shared E. T. Chan· 1 shared J. Timm· 1 shared J. Zephyr· 1 shared K. KosovrastiiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Ali

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1 paper

Recent·Most cited

BiochemistryJournal of Molecular BiologyPeer-reviewedMay 1, 2022

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

J. Zephyr, D. N. Rao, S. V. Vo…·C. A. Schiffer

The paper investigates how fluorination of HCV protease inhibitors improves resistance to the D168A variant by enabling alternate binding conformations through co-crystal structure analysis.

DOI 10.1016/j.jmb.2022.167503

structural biologyexperimental assay