Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment with TNF-alpha Antagonists
A. Vaisman-Mentesh, S. Rosenstein, M. Yavzori, Y. Dror, E. Fudim, B. Ungar, U. Kopylov, O. Picard, A. Kigel, S. Ben-Horin, I. Benhar, Y. Wine
The paper identifies the molecular features of anti-drug antibodies (ADA) against TNF-alpha antagonists and reveals their formation mechanism through a new bio-immunoassay.
bioRxiv · Dec 11, 2019Immunology