Author

A. L. Speelman

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Biochemistry· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

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A. Sarkar· 1 shared E. L. Carter· 1 shared J. B. Harland· 1 shared N. Lehnert· 1 shared S. W. Ragsdale· 1 shared

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1 shared paperBiochemistry

A. Sarkar

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1 paper

Recent·Most cited

BiochemistrybioRxivJun 22, 2020

Ferric Heme as a CO/NO Sensor in the Nuclear Receptor Reverbβ by Coupling Gas binding to Electron Transfer

S. W. Ragsdale, A. Sarkar, E. L. Carter…·N. Lehnert

This study shows that Rev-Erbβ functions as a CO/NO sensor by coupling gas binding to electron transfer, maintaining Fe3+ heme state for repressor activity and enabling redox changes upon gas binding.

DOI 10.1073/pnas.2016717118

humanexperimental assay