Author

A. Lapinaite

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1

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J. A. Doudna· 1 shared J. Cate· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiochemistry

J. A. Doudna

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1 paper

Recent·Most cited

Programmable RNA recognition using a CRISPR-associated Argonaute

A. Lapinaite, J. A. Doudna, J. Cate

This paper shows that modifying guide RNAs with 5-BrdU enhances the specificity and affinity of CRISPR-associated Argonaute RNPs for RNA targets, enabling single-nucleotide discrimination and RNA editing detection.

bioRxiv · Jan 19, 2018Biochemistry