Ivermectin repurposing for COVID-19 therapy: Safety and pharmacokinetic assessment of a novel nasal spray formulation in a pig model
J. Errecalde, A. Lifschitz, G. Vecchioli, L. Ceballos, F. Errecalde, M. Ballent, G. Marin, M. Daniele, E. Turic, E. Spitzer, F. Toneguzzo, S. Gold, A. Krolewiecki, L. Alvarez, C. Lanusse
This study evaluates the safety and pharmacokinetics of a nasal ivermectin spray in pigs, showing higher drug concentrations in nasal and lung tissues compared to oral administration.
bioRxiv · Oct 23, 2020 · PreprintPharmacology & Toxicology