Author

A. N. Conte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Burroughs· 1 shared A. T. Whiteley· 1 shared D. W. Bak· 1 shared E. M. Kibby· 1 shared E. Weerapana· 1 shared J. A. Vargas· 1 shared J. L. Meier· 1 shared K. D. Nance· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. M. Burroughs

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bacterial NLR-related proteins protect against phage

E. M. Kibby, A. N. Conte, A. M. Burroughs, T. A. Nagy, J. A. Vargas, L. Aravind, A. T. Whiteley

This study identifies bacterial NLR-related proteins that defend against phages, showing they share structural and functional features with eukaryotic NLRs and use a conserved signaling mechanism.

bioRxiv · Jul 19, 2022Microbiology

Conditional covalent lethality driven by oncometabolite accumulation

M. Perez, K. D. Nance, D. W. Bak, S. T. Gamage, S. S. Najera, A. N. Conte, W. M. Linehan, E. Weerapana, J. L. Meier

The paper identifies a covalent small molecule, MP-1, that exhibits FH-dependent cytotoxicity in HLRCC by targeting cysteine residues, including in TRMT1, and shows TRMT1 overexpression can rescue tRNA methylation inhibition.

bioRxiv · Apr 26, 2022Biochemistry