Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via inositol 1,4,5-trisphosphate receptors
T. Kozono, C. Jogano, W. Okumura, H. Sato, H. Matsui, T. Takagi, N. Okumura, T. Takao, T. Tonozuka, A. Nishikawa
This study shows that cleavage of Jaw1's C-terminal region by the signal peptidase complex enhances its ability to augment Ca2+ release via IP3Rs.
bioRxiv · Dec 10, 2022 · PreprintCell Biology