SARS-CoV-2 Omicron is specifically restricted in its replication in human lung tissue, compared to other variants of concern
O. Alfi, M. Hamdan, O. Wald, A. Yakirevitch, O. Wandel, E. Oiknine-Djian, B. Gvili, H. Knoller, N. Rozendorn, H. Golan Berman, S. Adar, O. Vorontsov, M. Mandelboim, Z. Zakay-Rones, M. Oberbaum, , D. Wolf
This study compares SARS-CoV-2 Omicron replication in human lung and nasal tissues to other variants, finding restricted replication in lungs and a stronger interferon response.
bioRxiv · Mar 31, 2022 · PreprintMicrobiology