Human nasal and lung tissues infected ex vivo with SARS-CoV-2 provide insights into differential tissue-specific and virus-specific innate immune responses in the upper and lower respiratory tract
O. Alfi, A. Yakirevich, O. Wald, O. Wandel, U. Izhar, E. Oiknine-Djian, Y. Nevo, S. Elgavish, E. Dagan, O. Madgar, G. Feinmesser, E. Pikarsky, M. Bronstein, O. Vorontsov, W. Jonas, , D. G. Wolf
This study compares SARS-CoV-2 and influenza virus infection in human nasal and lung tissues, revealing distinct innate immune responses in the upper and lower respiratory tract.
bioRxiv · Mar 8, 2021Microbiology