Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
A. Seshadri, A. Badrinarayanan
The paper investigates how mtDNA damage affects polymerase gamma activity and mtDNA stability in yeast, showing that exonuclease activity drives damage-induced mtDNA clearance.
bioRxiv · Mar 29, 2024Microbiology