A. Stephanou

A computational model of the spatiotemporal adaptation of tumor cells metabolism in a growing spheroid

This paper develops a computational model to simulate tumor spheroid metabolism, revealing spatiotemporal metabolic diversity and the role of acidity and pyruvate-lactate interactions in shaping tumor cell behavior.

Why the tumor cell metabolism is not that abnormal

This paper presents a theoretical model of tumor cell metabolism showing that the Warburg effect is a transient adaptation to environmental stress, not an inherent tumor characteristic.