Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome.
A. Szymula, R. D. Palermo, I. J. Groves, M. Ba abdullah, B. S. Holder, R. E. White
This paper shows EBNA-LP is essential for transforming naive B cells and facilitates transcription factor recruitment to the viral genome, with distinct effects on different B cell subsets.
bioRxiv · Aug 22, 2017Microbiology