Methicillin resistant Staphylococcus aureus emerged long before the introduction of methicillin in to clinical practice
C. P. Harkins, B. Pichon, M. Doumith, J. Parkhill, H. Westh, A. Tomasz, H. de Lencastre, S. D. Bentley, A. M. Kearns, M. T. Holden
This study shows that MRSA emerged in the mid-1940s, long before methicillin was introduced, due to prior use of first-generation beta-lactams.
bioRxiv · Mar 31, 2017Microbiology